Positions

Associate Professor, Pharmacology and Toxicology, Brody School of Medicine

Contact Info

cookebaileyj23@ecu.edu

Publications in VIVO

Co-author Network

Co-investigator Network

Jessica Cooke Bailey

member of

selected publications

article
- Performance of Polygenic Risk Scores for Primary Open-Angle Glaucoma in Populations of African Descent. JAMA ophthalmology. 143:7-14. 2025
- Genome-wide association analyses identify distinct genetic architectures for age-related macular degeneration across ancestries. Nature genetics. 56:2659-2671. 2024
- Association Between Fuchs Endothelial Corneal Dystrophy, Diabetes Mellitus, and Multimorbidity. Cornea. 42:1140-1149. 2023
- Diversity is key for cross-ancestry transferability of glaucoma genetic risk scores in Hispanic Veterans in the Million Veteran Program. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 28:413-424. 2023
- Importance of Diversity in Precision Medicine: Generalizability of Genetic Associations Across Ancestry Groups Toward Better Identification of Disease Susceptibility Variants. Annual review of biomedical data science. 6:339-356. 2023
- Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci. Nature genetics. 55:1116-1125. 2023
- Mechanosensitive ion channel gene survey suggests potential roles in primary open angle glaucoma. Scientific Reports. 13. 2023
- Mitochondrial TXNRD2 and ME3 Genetic Risk Scores Are Associated with Specific Primary Open-Angle Glaucoma Phenotypes. Ophthalmology. 130:756-763. 2023
- Note the Nuance-Examining the Association of Alzheimer-Protective APOE Variation With Risk for Age-Related Macular Degeneration. JAMA ophthalmology. 141:22-23. 2023
- T-cell receptor diversity in minimal change disease in the NEPTUNE study. Pediatric nephrology (Berlin, Germany). 38:1115-1126. 2023
- Development and Evaluation of a Rules-based Algorithm for Primary Open-Angle Glaucoma in the VA Million Veteran Program. Ophthalmic epidemiology. 29:640-648. 2022
- Diversity in Polygenic Risk of Primary Open-Angle Glaucoma. Genes. 14. 2022
- Glaucoma Genetic Risk Scores in the Million Veteran Program. Ophthalmology. 129:1263-1274. 2022
- Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye. JAMA. 325:753-764. 2021
- Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries. Nature Communications. 12. 2021
- Polygenic Risk Scores. Current protocols. 1. 2021
- The GGLEAM Study: Understanding Glaucoma in the Ohio Amish. International Journal of Environmental Research and Public Health. 18. 2021
- Association of APOE With Primary Open-Angle Glaucoma Suggests a Protective Effect for APOE 4. Investigative ophthalmology & visual science. 61. 2020
- Editorial: The Importance of Diversity in Precision Medicine Research. Frontiers in genetics. 11. 2020
- Progress, Not Perfection: Intraocular Pressure Genetic Risk Score Stratifies Clinically Relevant Primary Open-Angle Glaucoma Outcomes. Ophthalmology. 127:908-909. 2020
- AMISH EYE STUDY: Baseline Spectral Domain Optical Coherence Tomography Characteristics of Age-Related Macular Degeneration. Retina (Philadelphia, Pa.). 39:1540-1550. 2019
- Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. JAMA. 322:1682-1691. 2019
- Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis. JAMA ophthalmology. 137:1190-1194. 2019
- Bridging the Gaps in Personalized Medicine Value Assessment: A Review of the Need for Outcome Metrics across Stakeholders and Scientific Disciplines. Public health genomics. 22:16-24. 2019
- Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma. Scientific Reports. 8. 2018
- Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases. Nature Communications. 9. 2018
- Willingness to Participate in a National Precision Medicine Cohort: Attitudes of Chronic Kidney Disease Patients at a Cleveland Public Hospital. Journal of Personalized Medicine. 8. 2018
- A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium. Investigative ophthalmology & visual science. 57:4528-4535. 2016
- A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. Nature genetics. 48:134-43. 2016
- Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses. Investigative ophthalmology & visual science. 57:5046-5052. 2016
- Quality Control for the Illumina HumanExome BeadChip. Current protocols in human genetics. 90. 2016
- A common variant near TGFBR3 is associated with primary open angle glaucoma. Human molecular genetics. 24:3880-92. 2015
- An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects. PLOS ONE. 8. 2013
- A genome-wide association search for type 2 diabetes genes in African Americans. PLOS ONE. 7. 2012
- A genome-wide association study for diabetic nephropathy genes in African Americans. Kidney international. 79:563-72. 2011
- A single nucleotide polymorphism within the acetyl-coenzyme A carboxylase beta gene is associated with proteinuria in patients with type 2 diabetes. PLoS genetics. 6. 2010
- Serotype-specific differences in antigenic regions of foot-and-mouth disease virus (FMDV): a comprehensive statistical analysis. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 8:855-63. 2008

presentations

presentation

principal investigator on

co-principal investigator on

PFAS and Eye Health: Molecular Drivers of Ocular Disease at the Intersection of Environment and Health Equity awarded by North Carolina State University (NCSU) 2024 - 2026

investigator on

professional service activities

Ad Hoc Reviewer Nature CommunicationsNature MedicineInvestigative Ophthalmology & Visual ScienceAmerican Journal of OphthalmologyJAMA OphthalmologyMolecular Aspects of MedicineScientific Reports 2023

education and training

B.S. in Biology, Winthrop University
M.A. in Bioethics, Case Western Reserve University
Ph.D. in Molecular Medicine & Translational Science, Wake Forest University

awards and honors

Order of the Anchor Society, conferred by East Carolina University, 2025
North Coast Conference on Precision Medicine Cleveland Institute for Computational Biology Travel Award, conferred by North Coast Conference on Precision Medicine, 2023

preferred title

Associate Professor, Pharmacology & Toxicology, Center for Health Disparities

located in facility