The role of Ataxin1 in autoimmune demyelination
Grant
Overview
abstract
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This project deals with a novel, previously unknown role of ATXN1 as regulator of the immune response. ATXN1 mutations were previously recognized as causative of the neurodegenerative disease spinocerebellar ataxia type 1, but is only recently that we identified its influence on multiple sclerosis risk. We will use state of art of genomics methodologies to identify and characterize the role that ATXN1 plays in autoimmune demyelination.
date/time interval
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April 2022 - September 2023
awarded by