Positions

Professor, Chemistry, College of Arts and Sciences

Contact Info

allenwi@ecu.edu

252-328-9779

Publications in VIVO

Co-author Network

Co-investigator Network

William E Allen

selected publications

article
- Course-Based Undergraduate Research Experiences as a Community of Practice (CoP). The Journal of Chemical Education. 100:2520-2528. 2023
- Association between N-Terminal Pyrenes Stabilizes the Collagen Triple Helix. Journal of Organic Chemistry. 88:11885-11894. 2023
- Design and Implementation of an Organic to Analytical CURE Sequence. Journal of Chemical Education. 98:2199-2208. 2021
- Embedding Research Directly into the Chemistry Curriculum with an Organic to Analytical Sequence. Journal of Chemical Education. 98:2188-2198. 2021
- Synthesis of Redox-Active Fluorinated 5-Hydroxytryptophans as Molecular Reporters for Biological Electron Transfer. Chemical Communications. 2021
- Side-chain protonation states of a fluorescent arginine. The Journal of Organic Chemistry. 84:14407-14413. 2019
- Anion Binding by N-Protected Fluorescent Citrulline
  . 253rd ACS National Meeting and Exposition. 2017
- Excited-State Properties of Fluorescent Arginine: Toward Light-Promoted Cellular Penetration
  . 253rd ACS National Meeting and Exposition. 2017
- Fluorescent Derivatives of Arachidonic Acid: Tools for Studying the Anti-Cancer Activity of Prostaglandins
  . 253rd ACS National Meeting and Exposition. 2017
- Stabilizing the Collagen Triple Helix with a Ruthenium(II) Anchor
  . 253rd ACS National Meeting and Exposition. 2017
- Where the Glow Shouldn't Go: Fluorescent Arginine Inside of Membranes
  . 253rd ACS National Meeting and Exposition. 2017
- Anion Binding by Fluorescent Fmoc-Protected Amino Acids. Supramolecular Chemistry. 28:45-52. 2016
- Incorporation of Fluorophore-Cholesterol Conjugates into Liposomal and Mycobacterial Membranes. Bioorganic & Medicinal Chemistry. 24:1045-1049. 2016
- Enhancing Through-Membrane Transport of Anions with Synthetic Lipids; ORGN 270
  . 245th ACS National Meeting & Exposition. 2013
- Dimerization and Anion Binding of a Fluorescent Phospholipid Analogue. Journal of Organic Chemistry, The. 77:6615-6619. 2012
- Binding of Carboxylic Acids by Fluorescent Pyridyl Ureas. Journal of Organic Chemistry, The. 2010
- Fluorous Effects in Amide-Based Receptors for Anions. Journal of Organic Chemistry, The. 74:3706-3710. 2009

presentations

presentation

principal investigator on

Organic Fund Award awarded by Department of Chemistry, ECU 2015
Large-Scale Chemical Purification via Molecular Recognition awarded by Syngenta Crop Protection, Inc. 2007 - 2009
Large-Scale Chemical Purification via Molecular Recognition awarded by Syngenta Crop Protection, Inc. 2008
Hosts for an Uninvited Guest: Binding PFOS with Designed Ligands awarded by Division of Research and Graduate Studies, ECU 2007
A Recyclable System for Detection of Phosphate in Water awarded by Research and Creative Activity Committee, ECU 2005
Fluorescent Mimics of Phosphotyrosine as Probes for Intracellular Signal Transmission awarded by Research Corporation 2002 - 2004
Light-Activated Membrane Probes: Potential Tools for Controlling Cell Signaling awarded by GlaxoSmithKline 2002
First Circular Dichroism Spectrometer for East Carolina University awarded by North Carolina Biotechnology Center 2002
Light-Activated Membrane Probes: Potential Tools for Controlling Cell Signaling awarded by GlaxoSmithKline plc. 2001
Fluorescent Mimics of Phosphotyrosine as Probes for Intracellular Signal Transmission awarded by Research Corporation 2000
Controlling Chemical Communication Inside the Cell awarded by Research and Creative Activity Committee, ECU 2000
Measuring Chloride Ion Concentrations in Bodily Fluids awarded by Research and Creative Activity Committee, ECU 1998

co-principal investigator on

Collagen Takes a "Nap": Interrupting the (Pro-Hyp-Gly)n Repeat Sequence of Collagen Model Peptides with a Naphthalimide Fluorophore awarded by ECU Office of Undergraduate Research (URCA Award) 2025
Never Say Forever: PFAS Capture Design awarded by ECU Office of Undergraduate Research (URCA Award) 2025
Collagen, interrupted: synthesis and analysis of fluorescent collagen awarded by The Office of Undergraduate Research, ECU (URCA Award) 2024
Illuminating Collagen: Exploring Triple Helix Formation with Fluorescence Kinetics awarded by The Office of Undergraduate Research, ECU (URCA Award) 2023
Effects of Localized pH Changes on Enamelin Phosphoserine Stability awarded by The Office of Undergraduate Research, ECU (URCA Award) 2022
Detecting Abasic Sites in DNA with Guanine Analogues awarded by The Office of Undergraduate Research, ECU (URCA Award) 2021
Water-Soluble 'SNAP' Peptides awarded by Department of Chemistry, ECU (PURC Award) 2020
Inhibition of Ice Crystallization Using Fluorescent Antifreeze Peptides awarded by Department of Chemistry, ECU (PURC Award) 2019
Chemistry Undergraduate Research Experience (CURE) Award awarded by Department of Chemistry, ECU 2016
Undergraduate Research and Creative Activity (URCA) Award awarded by The Office of Undergraduate Research, ECU 2016
Undergraduate Research and Creative Activity (URCA) Award awarded by The Office of Undergraduate Research, ECU 2015
Chemistry Undergraduate Research Experience (CURE) Award awarded by Department of Chemistry, ECU 2015
Scholarly Activity Awards for Students (SAAS) awarded by The Honors College, ECU 2014
Chemistry Undergraduate Research Experience (CURE) Award awarded by Department of Chemistry, ECU 2014
Travel Awards (ACS National Meeting, Denver, CO, March 2015) awarded by The Office of Undergraduate Research, ECU 2014
Undergraduate Research and Creative Activity (URCA) Award awarded by The Office of Undergraduate Research, ECU 2014
Undergraduate Research and Creative Activity (URCA) Award awarded by The Office of Undergraduate Research, ECU 2013
Undergraduate Research and Creative Activity (URCA) Award awarded by The Office of Undergraduate Research, ECU 2012
Departmental Research Award (Book Funds) awarded by Department of Chemistry, ECU 2012
Departmental Research Award (Book Funds) awarded by Department of Chemistry, ECU 2011
Undergraduate Research and Creative Activity (URCA) Award awarded by The Office of Undergraduate Research, ECU 2010
Upgrade of NMR Equipment awarded by National Science Foundation 2000 - 2003

investigator on

Team Experiences and Mentoring Strategies for Undergraduate Research (TEaMS-UR) awarded by NSF - National Science Foundation 2020 - 2026
RUI: Development of Unnatural Tryptophan Derivatives to Expand Tryptophan Function and to Study Biological Catalysis awarded by National Science Foundation (NSF) 2020 - 2023
ChemCUREs: Increased access to authentic research for undergraduate Chemistry students through Course-based Undergraduate Research Experiences - SUPPLEMENT awarded by NSF - National Science Foundation 2018 - 2021
Ischemic Vascular Disease: Determining Acid/Base Status in a 'SNAP' awarded by Biomaterials Research Cluster, ECU 2020 - 2021

professional service activities

REVIEWER--Research on Chemical Intermediates Manuscript ID: 6869b821-237b-4767-b0e2-f23b348ac7ba (10/25/2025) 2025
REVIEWER--Current Organic Chemistry Manuscript No. BMS-COC-2023-329 (2/5/2024) 2023
Judge--NC Region I Science and Engineering Fair Hosted by ECU (02/25/2023) 2022
REVIEWER--Journal of Organic Chemistry Manuscript ID: jo-2019-020912 (08/16/2019) 2019
REVIEWER--Bioorganic and Medicinal Chemistry Manuscript No. BMC 2019-413 (04/17/2019) 2018
Judge--Northeast Regional Science and Engineering Fair Hosted by ECU (02/16/2019) 2018
REVIEWER--ChemistrySelect Manuscript No. slct.201800985 (04/09/2018) 2017
REVIEWER--Symmetry Manuscript ID: symmetry-261907 (01/07/2018) 2017
REVIEWER--Love's General, Organic, and Biochemistry (Chapters 13-17) 2017
REVIEWER--Supramolecular Chemistry Manuscript ID GSCH-2016-0100.R1 (09/03/2016) 2016
REVIEWER--The Journal of Organic Chemistry Manuscript ID: jo-2016-01969 (09/02/2016) 2016
The Journal of Organic Chemistry Manuscript No. ; jo-2012-01450b 2012

awards and honors

"Honored Instructor Award", conferred by Campus Living/Residence Hall Assoc., 2022
ECU Panhellenic Outstanding Educator Award, conferred by Panhellenic Association, 2022
Board of Governors Award for Excellence in Teaching, conferred by ECU Office for Faculty Excellence, 2019
Board of Governor's Distinguished Professor for Teaching Award, conferred by ECU Office for Faculty Excellence, 2001

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