
Positions
- Associate Professor, Physics, College of Arts and Sciences
- Contact Info
Nathan E Hudson
Affiliation
Publications
selected publications
presentations
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presentation
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Crossing the Coagulation Rubicon: Tracing the (patho)physiological ramifications of the fibrinogen to fibrin transition from single molecules to blood clot structures and lysis
, Nationwide Children's Hospital Colloquium 2025 - Quantifying Tension and Exploring its Role in determining Blood Clot Fate, Rutgers Engineering Colloquium 2024
- Chorographic Mapping of Human Fibrinogen Structures in Solution, 27th International Fibrinogen Workshop 2024
- What is the diameter of a fibrin fiber? , 27th International Fibrinogen Workshop 2024
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Examining the effect inherent and applied tension have on fibrinolysis
, 11th Symposium on Hemostasis 2024 -
Testing the congruence of fibrin fiber diameters across varying biochemical conditions and techniques
, 11th Symposium on Hemostasis 2024 -
Structural Dynamism of Human Fibrinogen
, 11th Symposium on Hemostasis 2024 - Probing the polymerization and structure of a blood clot, Computational Medicine and Bioinformatics Colloquium 2023
- Fibrinogen and Fibrin: A Story for the Ages, ECU Protein Biophysics Workshop 2023
- Engineering Principles of Blood Clot Formation and Dissolution, Engineering and Physics Colloquium 2023
- Structural and Biomechanical Features of Blood Clots, Physics Colloquium 2023
- Developing a Mechanistic Understanding of Fibrin Fiber Digestion During Fibrinolysis, 2022 Hemostasis Gordon Research Conference 2022
- Evaluating the Use of Turbidimetry for Determining Fibrin Fiber Diameter, 2022 Hemostasis Gordon Research Conference 2022
- Fibrinogen Farming: Exploring Transient Recombinant Expression and Affinity-Based Purification of Human Fibrinogen, 2022 Hemostasis Gordon Research Conference 2022
- Towards a Robust Recombinant Expression and Purification Process for Human Fibrinogen, 26th International Fibrinogen Research Society Worskshop 2022
- Microscale Mechanisms Regulating Fibrin Clearance During Fibrinolysis, AHA Vascular Discovery: from Genes to Medicine Scientific Sessions 2022 2022
- 3D Modeling of Fibrinogen's D region using Cryogenic Electron Microscopy, East Carolina University Research and Creative Achievement Week 2022
- A New Model for Fibrinolysis - The End of a 50 Year Debate, East Carolina University Research and Creative Achievement Week 2022
- Altered Fibrinolysis by Fluorophore Labeling, East Carolina University Research and Creative Achievement Week 2022
- Assessing and Developing Protocols for Purifying Fibrinogen From Human Blood Plasma, East Carolina University Research and Creative Achievement Week 2022
- Comparing Fibrin Structure in Blood Clots Impacted by Flow Rate, East Carolina University Research and Creative Achievement Week 2022
- Cryo-EM Sample Preparation Using Ultrasonic Vibrations, East Carolina University Research and Creative Achievement Week 2022
- Evaluating the Use of Turbidimetry for Analyzing Fibrin Fibers, East Carolina University Research and Creative Achievement Week 2022
- Fabricating Rapid Transient Recombinant Expression and Affinity Chromatography Systems for Human Fibrinogen, East Carolina University Research and Creative Achievement Week 2022
- Novel Affinity-based Fibrinogen Purification Strategies, 2021 Annual BMES Meeting 2021
- Assessing Current Turbidimetric Approaches in Determining Fibrin Fiber Properties, International Fibrinogen Research Society Mini-Symposium 2021
- Fibrinogen -C Connector is a Major Contributor to the Mechanical Strength of Fibrin Fibers, International Fibrinogen Research Society Mini-Symposium 2021
- Inherent Polymer Tension Regulates the Enzymatic Breakdown of Blood Clots, Endeavor Research 2nd Webinar on Chemistry 2021
- Mechanisms of Fibrinolysis of Fibrin Fibers, International Fibrinogen Research Society Mini-Symposium 2021
- Quantifying the Inherent Tension in Fibrin Fibers and Understanding Its Role in Fibrinolytic Clearance, International Fibrinogen Research Society Mini-Symposium 2021
- A New Model for Fibrinolysis, East Carolina University Research and Creative Achievement Week 2021
- Effects of N-linked Glycans on Fibrinogen Turbidity Assay, East Carolina University Research and Creative Achievement Week 2021
- Using Cryo-Electron Microscopy to Determine the 3-Dimensional Structure of Fibrinogen, East Carolina University Research and Creative Achievement Week 2021
- Measuring the Effects of Fibrinogen Glycosylations on Fibrin Polymerization using Turbidity, SoDM Celebration of Research and Scholarship (CORAS) 2020 2021
- Resolving Structural Changes In Fibers During Fibrinolysis, 65th Annual Biophysical Society Meeting 2021
- The Validity of Current Turbidimetric Approaches in Determining Fibrin Diameter, SoDM Celebration of Research and Scholarship (CORAS) 2020 2021
- Resolving Structural Changes During the Digestion of Fibrin Fibers, The Triangle Cytoskeleton Meeting 2020 2020
- Reverse Engineering Natural Blood Clot Biopolymers, STEM at Starlight Biomaterials 2020
- Intrinsically Unfolded Alpha-C Region Of Fibrinogen is Major Contributor to Mechanical Strength of Fibrin Fibers, 64th Annual Biophysical Society Meeting 2020
- Unexpected, Tension-Dependent Mechanisms Govern Network Clearance During Fibrinolysis, 64th Annual Biophysical Society Meeting 2020
- Investigation of the interplay between blood and thrombus mechanical properties: A 3D fluid-solid interaction model, Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C2019) 2019
- A computational study of mechanical characteristic of a thrombus, East Carolina University Research and Creative Achievement Week 2019
- Determining the Energy Landscape of the Integrin-iC3b Bond Under Dynamic Force, East Carolina University Research and Creative Achievement Week 2019
- Fluorescent Protein Cell Sorting as a Method to Isolate a Stable Cell Line, East Carolina University Research and Creative Achievement Week 2019
- Investigating What Effect Flow Has on Fibrin Properties using Microfluidics, East Carolina University Research and Creative Achievement Week 2019
- Investigating the C Connector for Roles in Fibrin Extensibility and Polymerization, East Carolina University Research and Creative Achievement Week 2019
- Mechanics Regulating the Dissolution of Fibrin in Blood Clots, East Carolina University Research and Creative Achievement Week 2019
- Production of Monomeric Fibrin the does not Polymerize, East Carolina University Research and Creative Achievement Week 2019
- Fibrin Density and Tension Regulates Fibrinolytic Susceptibility, 63rd Annual Biophysical Society Meeting 2019
- Characterization of Engineered Fibrinogen to Understand the Role of the & C Region in Fibrin Mechanical Properties and Polymerization during Haemostasis, Biomedical Engineering Society (BMES) Annual Meeting 2018
- Mechanics Governing Fibrin Fibers During Dissociation of Blood Clots, 11th Biennial Carolina Biophysics Symposium 2018
- Probing the C Connector's Role in Fibrin Fiber Mechanics, 11th Biennial Carolina Biophysics Symposium 2018
- Elongation of Fibrin Fibers during Fibrinolysis, 25th International Fibrinogen and 3rd Factor XIII Workshop 2018
- Examining the C Connector and its role on Fibrin Polymerization and Extensibility, 25th International Fibrinogen and 3rd Factor XIII Workshop 2018
- A Biophysical Approach to Understanding Fibrin's Extensibility, East Carolina University Research and Creative Achievement Week 2018
- Effects of Mechanical Manipulation on Cancer Cell Motility and Proliferation, East Carolina University Research and Creative Achievement Week 2018
- Fibrin Network Alignment Within Different Flow Rates, East Carolina University Research and Creative Achievement Week 2018
- Fibrinolysis and the Affects of Cross-Linking Within a Network, East Carolina University Research and Creative Achievement Week 2018
- How fibrin fiber transection during fibrinolysis affects the rate of further degradation, East Carolina University Research and Creative Achievement Week 2018
- Testing the correlation between mechanical properties measured in fibrin and the repeating amino acid sequence in the C region of fibrinogen, East Carolina University Research and Creative Achievement Week 2018
- Yeast Antibody-Antigen Bond Engineering Using Centrifuge Force Microscopy, East Carolina University Research and Creative Achievement Week 2018
- Von Willebrand Factor, a Force-Selective Platelet Binder and Factor VIII Carrier, 62nd Annual Biophysical Society Meeting 2018
- Biophysical studies of Platelet-Fibrin Interactions, East Carolina University Research and Creative Achievement Week 2017
- CD and LD Fibrin Spectroscopy, East Carolina University Research and Creative Achievement Week 2017
- Centrifuge Force Microscope Resolution Enhancement, East Carolina University Research and Creative Achievement Week 2017
- Fibrinolysis Within a Fibrin Network, East Carolina University Research and Creative Achievement Week 2017
- Truncation of tandem repeats in fibrin's C region: how it affects the elasticity, extensibility, and polymerization of fibrin, East Carolina University Research and Creative Achievement Week 2017
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Research
principal investigator on
- Collaborative Research: The Role of Tension in the Digestion of Blood Clots. awarded by NSF - National Science Foundation 2024 - 2027
- How do early stages of fibrin fiber assembly affect clot structure and lysis awarded by DHHS - National Institutes of Health (NIH) 2024 - 2027
- Identifying the function of the Fibrin(ogen) alpha-C connector region awarded by DHHS - National Institutes of Health (NIH) 2019 - 2023
- Open Access Publishing Support Fund Award awarded by Academic Affairs and Health Sciences and University Libraries 2021
- Pilot data on the mechanical properties of a Fibrinogen aC domain variant for an NSF proposal awarded by Wake Forest University 2018 - 2020
- Development of monomeric fibrin molecules to enable rationally-designed fibrin targeting strategies awarded by THCAS 2018 - 2019
- Open Access Publishing Support Fund Award awarded by Academic Affairs and Health Sciences and University Libraries 2016
co-principal investigator on
investigator on
Service
professional service activities
- Abstract Reviewer for the 2025 ISTH Congress Reviewed 25 abstracts for the 2025 International Society on Thrombosis and Haemostais (ISTH) meeting. 2024
- British Journal of Haematology Peer reviewed article for the British Journal of Haematology 2024
- Biophysical Journal Peer reviewed article for the journal Biophysical Journal 2024
- Journal of Clinical Medicine Peer reviewed article for the journal Journal of Clinical Medicine 2024
- Research and Practice in Thrombosis and Hemostasis Peer reviewed article for the journal Research and Practice in Thrombosis and Hemostasis 2024
- Acta Biomateria Peer reviewed article for the journal Acta Biomateria 2023
- Reviewer for: JoVE Peer reviewed article for the Journal of Visualized Experiments (JoVE) 2023
- Innaugural Protein Biophysics Workshop Organized the Innaugural Protein Biophysics Workshop 2023
- Biophysical Society Early Careers Committee Plan and coordinate events as part of the biophysical society early careers committee. Service consists of two meetings annually (one in person at the BPS meeting) and one over skype where outreach events are planned for early career scientists 2016 - 2022
- Wrote Recommendation Letters for nine students Students applied for medical school, graduate school, jobs, and summer programs. 2022
- ACS Bio and Med Chem Peer reviewed article for the journal ACS Bio and Med Chem 2021
- Mechanical Behavior of Biomedical Materials Peer reviewed article for the journal Mechanical Behavior of Biomedical Materials 2021
- Member of the Board of Councilors for the International Fibrinogen Research Society Member of the Board of Councilors for the International Fibrinogen Research Society 2021
- 66th Annual Biophysical Society Meeting Organized and the panel of the graduate student virtual career panel. The panel focussed on career transitions in science. 2021
- Biophysical Reviews Peer reviewed article for the journal Biophysical Reviews 2021
- NSF Proposal reviewer NSF EBMS Panel 2020
- 65th Annual Biophysical Society Meeting Organized and moderated the panel of the graduate student virtual career panel, which happened prior to the biophysical society meeting annual meeting. ; The panel focussed on career transitions in science. 2020
- 64th Annual Biophysical Society Meeting Organized the panel of the graduate student breakfast at the biophysical society meeting. ; The panel focussed on career transitions in science. 2019
- Reviewer PNAS Reviewer for the journal: Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2019
- Deutsche Forschungsgemeinschaft (German Research Foundation) Grant Application reviewer for the Deutsche Forschungsgemeinschaft (German Research Foundation) 2018 - 2019
- Deutsche Forschungsgemeinschaft (DFG) German Research Foundation Grant Application reviewer for the Deutsche Forschungsgemeinschaft (DFG)German Research Foundation 2018
- External Review for the University of Sydney External Dissertation Reviewer for the University of Sydney, Australia 2018
- 63rd Annual Biophysical Society Meeting Organized and moderated the panel of the graduate student breakfast at the biophysical society meeting. The panel focussed on career transitions in science. I found speakers for the panel and kept up a continuous dialogue with the panelists in between student questions 2018
- Organized the 2019 Sigma Pi Sigma Induction Ceremony Organized and hosted the 2019 Sigma Pi Sigma induction ceremony for the ECU Society of Physics Students. 2018
- Scientific Advice Columnist I was invited to write an advice column on how to negotiate a startup package for the biophysical society. ; The column was published in the biophysical society newsletter. 2018
- High Point University Department of Physics Spent the day at High Point University discussing potential collaborations and then gave an invited lecture. 2018
- Chaired the session on fibrinolysis 25th International Fibrinogen and 3rd Factor XIII Workshop committee chair on fibrinolysis 2017
- ECU Chemistry Colloquium Spent the day meeting with chemistry department faculty members and discussing potential collaborations and then gave an invited lecture. 2017
- Guest Editor: PNAS Guest Edior for the journal: Proceedings of the National Academy of Sciences of the United States of America (PNAS) 2017
- Reviewer for: Journal of Thrombosis and Haemostasis Peer reviewed article for the Journal of Thrombosis and Haemostasis 2017
- Reviewer for: Research and Practice in Thrombosis and Haemostasis Peer reviewed article for the journal Research and Practice in Thrombosis and Haemostasis 2016 - 2017
- 62nd Annual Biophysical Society Meeting Organized the panel of the graduate student breakfast at the biophysical society meeting. The panel focussed on career transitions in science. 2017
- Research at Crave Presented Scientific Research at a Local Greenville Scientific Gathering 2016