Positions

Associate Professor, Foundational Sciences, School of Dental Medicine

Contact Info

muratar16@ecu.edu

252-737-7228

Publications in VIVO

Co-author Network

Co-investigator Network

Ramiro Mendonca Murata

member of

ADEA 2010
American Society of Pharmacognosy - ASP 2010
AADR 2005
IADR 2005

selected publications

article
- A dual pharmacological effect of escitalopram on alveolar bone loss in periodontitis
  . International immunopharmacology. 174. 2026
- Correlation between pre-extraction periodontal diagnosis and peri-implant microbiome for patients treated with implant-retained overdenture - A retrospective cohort pilot study. PLOS ONE. 20. 2025
- Impact of TiF Varnish on the Oral Biofilm Microbiome in High-Caries-Risk Patients. JDR clinical and translational research. 2025
- Resveratrol alters oral biofilm in vitro and in vivo. Journal of dentistry. 152. 2025
- Anadenanthera colubrina regulated LPS-induced inflammation by suppressing NF-B and p38-MAPK signaling pathways. Scientific Reports. 14. 2024
- BAFF neutralization impairs the autoantibody-mediated clearance of dead adipocytes and aggravates obesity-induced insulin resistance. Frontiers in immunology. 15. 2024
- Bioactive Compounds Enhance the Biocompatibility and the Physical Properties of a Glass Ionomer Cement. Journal of functional biomaterials. 15. 2024
- Cunninghamella echinulata DSM1905 biofilm-based L-asparaginase production in pneumatically-driven bioreactors. PLOS ONE. 19. 2024
- Cytotoxicity, pro-inflammatory cytokines gene expression and antioxidant activity of extract treated with active charcoal. Natural product research. 1-5. 2024
- Editorial: The interaction between the oral microbiota and systemic diseases. Frontiers in dental medicine. 5. 2024
- Experimental Periodontitis Increases Anxious Behavior and Worsens Cognitive Aspects and Systemic Oxidative Stress in Wistar Rats. Clinical and experimental dental research. 10. 2024
- Fear of the COVID-19 vaccine in a public healthcare system and university setting. PLOS ONE. 19. 2024
- Monoterpene antifungal activities: evaluating geraniol, citronellal, and linalool on biofilm, host inflammatory responses, and structure-activity relationships. Frontiers in Pharmacology. 15. 2024
- Score of fear of COVID-19 and physical activity level are related to the habitual consumption of dietary supplements. PLOS ONE. 19. 2024
- Syzygium aromaticum essential oil and its major constituents: Assessment of activity against Candida spp. and toxicity. PLOS ONE. 19. 2024
- Food preferences and periodontal status of adults assisted by a public health care system. PLOS ONE. 18. 2023
- Identification of the Neoaspergillic Acid Biosynthesis Gene Cluster by Establishing an CRISPR-Ribonucleoprotein Genetic System in. ACS omega. 8:16713-16721. 2023
- Racial and ethnic disparities in periodontal health among adults seeking dental care in rural North Carolina communities: A retrospective study. Journal of Periodontology. 94:364-375. 2023
- Fatty acids composition and in vivo biochemical effects of Aleurites moluccana seed (Candlenut) in obese wistar rats. Diabetology & metabolic syndrome. 14. 2022
- Outer Membrane Proteins 29 and 29 Paralogue Induce Evasion of Immune Response. Frontiers in oral health. 3. 2022
- (Vell.) Brenan as an inhibitor of HIV-1 BaL infection. Natural product research. 1-5. 2021
- Association between Chronotype and Nutritional, Clinical and Sociobehavioral Characteristics of Adults Assisted by a Public Health Care System in Brazil. Nutrients. 13. 2021
- Influence of Micronutrient Intake, Sociodemographic, and Behavioral Factors on Periodontal Status of Adults Assisted by a Public Health Care System in Brazil: A Cross-Sectional Multivariate Analysis. Nutrients. 13. 2021
- Knowledge to action: Integrating evidence-based practice into online PBL cases during COVID-19. Journal of dental education. 2021
- Streamlining the dental care during COVID-19 pandemic: updated clinical recommendations and infection control management framework. Brazilian oral research. 35. 2021
- Yeast Beta-Glucans Ingestion Does Not Influence Body Weight: A Systematic Review and Meta-Analysis of Pre-Clinical Studies. Nutrients. 13. 2021
- Yeast-Host Interactions: Modulates Virulence Factors of and Inflammatory Response. Frontiers in Pharmacology. 12. 2021
- Abilities of -Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells. Advances in biological regulation. 75. 2020
- Bioactive Dental Adhesive System With -Farnesol: Effects on Dental Biofilm and Bonding Properties. Frontiers in bioengineering and biotechnology. 8. 2020
- Biological and social aspects of Coronavirus Disease 2019 (COVID-19) related to oral health. Brazilian oral research. 34. 2020
- Abilities of berberine and chemically modified berberines to inhibit proliferation of pancreatic cancer cells. Advances in biological regulation. 71:172-182. 2019
- Abilities of berberine and chemically modified berberines to interact with metformin and inhibit proliferation of pancreatic cancer cells. Advances in biological regulation. 2019
- Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals. Advances in biological regulation. 72:22-40. 2019
- derivatives as inhibitors of HIV-1 BaL infection. Natural product research. 1-6. 2019
- Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cells-Power of nutraceuticals. Advances in biological regulation. 67:190-211. 2018
- Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of and Inflammatory Host Response. International journal of dentistry. 2018. 2018
- In Vivo Antifungal Activity of Monolaurin against Candida albicans Biofilms. Biological & pharmaceutical bulletin. 41:1299-1302. 2018
- Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals. Advances in biological regulation. 69:16-34. 2018
- Isoflavonoids from Brazilian red propolis down-regulate the expression of cancer-related target proteins: A pharmacogenomic analysis. Phytotherapy research : PTR. 2018
- Metformin influences drug sensitivity in pancreatic cancer cells. Advances in biological regulation. 2018
- Candida albicans stimulates Streptococcus mutans microcolony development via cross-kingdom biofilm-derived metabolites. Scientific Reports. 7. 2017
- Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs. Aging. 9:1477-1536. 2017
- Oral microbe-host interactions: influence of -glucans on gene expression of inflammatory cytokines and metabolome profile. BMC microbiology. 17. 2017
- Review of flavonoids: A diverse group of natural compounds with anti-Candida albicans activity in vitro. Archives of oral biology. 76:76-83. 2017
- Antifungal Activity of Alkaloids Against Candida albicans. Journal of the California Dental Association. 44:493-8. 2016
- Effects of COlaser irradiation on matrix-rich biofilm development formation-an in vitro study. PeerJ. 4. 2016
- In Vitro and In Vivo Antifungal Activity of Lichochalcone-A against Candida albicans Biofilms. PLOS ONE. 11. 2016
- In vitro evaluation of antifungal activity of monolaurin against Candida albicans biofilms. PeerJ. 4. 2016
- -Glucans (Saccharomyces cereviseae) Reduce Glucose Levels and Attenuate Alveolar Bone Loss in Diabetic Rats with Periodontal Disease. PLOS ONE. 10. 2015
- Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model. PLOS ONE. 10. 2015
- The changing role of HIV-associated oral candidiasis in the era of HAART. Journal of the California Dental Association. 43:87-92. 2015
- Anti-HIV-1 activity of flavonoid myricetin on HIV-1 infection in a dual-chamber in vitro model. PLOS ONE. 9. 2014
- Coriandrum sativum L. (Coriander) essential oil: antifungal activity and mode of action on Candida spp., and molecular targets affected in human whole-genome expression. PLOS ONE. 9. 2014
- Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans. Caries research. 45:327-35. 2011
- Effects of 7-epiclusianone on Streptococcus mutans and caries development in rats. Planta medica. 77:40-5. 2011
- Antiproliferative effect of benzophenones and their influence on cathepsin activity. Phytotherapy research : PTR. 24:379-83. 2010
- Influence of cranberry proanthocyanidins on formation of biofilms by Streptococcus mutans on saliva-coated apatitic surface and on dental caries development in vivo. Caries research. 44:116-26. 2010
- Inhibition of Streptococcus mutans biofilm accumulation and development of dental caries in vivo by 7-epiclusianone and fluoride. Biofouling. 26:865-72. 2010
- Antimicrobial activity of Rheedia brasiliensis and 7-epiclusianone against Streptococcus mutans. Phytomedicine : international journal of phytotherapy and phytopharmacology. 15:886-91. 2008
- Inhibitory effects of 7-epiclusianone on glucan synthesis, acidogenicity and biofilm formation by Streptococcus mutans. FEMS microbiology letters. 282:174-81. 2008
- Is dental caries reaching epidemic proportions in Brazil?. Nature Reviews Immunology. 7. 2007
- Effects of Mikania genus plants on growth and cell adherence of mutans streptococci. Journal of ethnopharmacology. 97:183-9. 2005
- Effect of a new variety of Apis mellifera propolis on mutans Streptococci. Current microbiology. 41:192-6. 2000

presentations

presentation

principal investigator on

Candida-Host interactions: impact on the host pro- and anti-viral restrictions factors awarded by DHHS - National Institutes of Health (NIH) 2021 - 2024
Oral Fungal-Host Interactions restrict viral replication. awarded by REDE Research and Creative Activity Award 2020 - 2021
Saliva - Antibody and Virus Early Detection (SAVED) Project awarded by UNC System COVID-Related Grant Activity Award 2020 - 2021
The University of North Carolina Center for AIDS Research awarded by University of North Carolina at Chapel Hill (UNC-CH) 2018 - 2019
Exploiting Interspecies/Interkingdom Communication for the discovery and development of Novel Natural Products Antifungal Therapeutics. awarded by University of Southern California (USC) 2016 - 2018

investigator on

Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools awarded by University of Florida (UF) 2023 - 2026

professional service activities

AADR/IADR Scientific Group Pharmacology / Therapeutics / Toxicology Immediate Past President 2019
IADR Scientific Group Pharmacology / Therapeutics / Toxicology Scientific Program Chair 2018 - 2019

credentials

Dental License

located in facility