Co-author Network
Map of Science
Co-investigator Network
member of
- Sigma Xi 1993 - 2016
- American Chemical Society 1993
Positions
- Professor, Chemistry, College of Arts and Sciences
- Contact Info
- 252-328-9790
Colin Burns
Affiliation
Publications
selected publications
presentations
-
presentation
-
IDENTIFICATION OF 15-DEOXY--PROSTAMIDE J MOLECULAR TARGETS IN B16F10 MURINE MELANOMA CELLS
, Carolina Cannabinoid Collaborative Annual Conference -
Therapeutic benefits of the endocannabinoid metabolite 15dPMJ2 as a monotherapy and in combination with immune checkpoint inhibitors
, Carolina Cannabinoid Collaborative Annual Conference -
IDENTIFICATION OF 15-12,14 DEOXY--PROSTAMIDE J MOLECULAR TARGETS IN B16F10 MURINE MELANOMA CELLS
, Carolina Cannabinoid Collaborative Annual Conference -
EXPLORING THE ROLE OF PGC1 IN 15d-PMJ2 CYTOTOXICITY IN MELANOMA SKIN CANCER
, Carolina Cannabinoid Collaborative Conference -
Physical Characterization and Cellular Testing of Polymeric Micelle Formulations for Intravenous Delivery of Hydrophobic Anticancer Drugs
, ECU Research and Creative Achievement Week -
Separation and Quantification of 15d-PMJ2 in Micelle Samples as an Anti-Cancer Therapeutic Using LC-MS/MS
, ECU Research and Creative Achievement Week -
Structural and quantitative analysis of the prostamide 15d-PMJ2 by NMR and computational studies
, ECU Research and Creative Achievement Week - I-Corps Healthcare Pitch Challenge (oral presentation), I-Corps Healthcare Pitch Challenge
- A Literature and Experiment Based Evaluation of Synthesis Techniques for Prothymosin-alpha Derived Peptides, ECU Research and Creative Achievement Week
- Biophysical studies of the intrinsically disordered protein prothymosin-alpha, 2017 Southeastern Regional Meeting of the American Chemical Society (SERMACS)
- Characterizing Micelles Through Spectroscopy and the Synthesis of Arachidonylethanolamide, Summer Research Undergraduate Symposium: REU in Chemistry and Biochemistry
- Claradele Pharmaceuticals, NC BIOTECH Venture Challenge (Statewide)
- Design and Quantitation of Membrane Binding Lipid Anchors, 63rd Southern Regional Meeting of the American Chemical Society
- Evaluating the biocompatibility of micelles in melanoma cells, ECU Research and Creative Achievement Week
- Examination of Peptide-Copper Complexes by Circular Dichroism; A First Step in Creating a CD Database for Metal-Peptide Complexes, ECU Research and Creative Achievement Week
- Micellar delivery of the immunotherapeutic 15-deoxy-D12,14-prostamide J2 for treatment of colon cancer, SouthEastern Regional Meeting of the American Chemical Society (SERMACS)
- Optimization and Evaluation of Pluronic F127 Micelles for Cancer Drug Delivery Applications, ECU Research and Creative Achievement Week
- Prothymosin-alpha: Features of the Protein that Contribute to its Anti-HIV Activity, ECU Research and Creative Achievement Week
- Quantitating Zinc Deposition in the ESI Source during Zinc-Peptide Analysis, 57th ASMS Conference on Mass Spectrometry
- Structural Modification of the Chemotherapeutic Anandamide: Designing Anti-Cancer Agents and Investigating Their COX-2 Metabolic Products, American Association for Cancer Research Annual Meeting
- Synthesis and Cytotoxic Evaluation of 15-deoxy-Prostamide J2 and Related Derivatives, 72nd Southeastern Regional Meeting of the American Chemical Society (SERMACS)
- Synthesis and Cytotoxic Evaluation of 15deoxy-Prostamide J2 and Related Derivative 15-deoxy-Prostamide J2-Arvanil, SouthEastern Regional Meeting of the American Chemical Society (SERMACS)
- Targeting Multiple Cancer Types by Micellar Delivery of the Immunotherapeutic 15-deoxy-12,14-Prostamide J2, North Carolina Biotechnology Flash Grant Impact Showcase
- The Use of Free Radicals to Study Zinc Binding in the Prion Protein, ECU Research and Creative Achievement Week
- Thermodynamic Investigations into Copper Binding in the N-Terminal Region of the Prion Protein at Low Copper Loading, ECU Research and Creative Achievement Week
-
Research
principal investigator on
- Targeting Multiple Cancer Types by Micellar Delivery of the Immunotherapeutic 15-deoxy-D12,14-Prostamide J2 awarded by NCBC - North Carolina Biotechnology Center 2022 - 2024
- The role of flexibility in determining the metal binding affinity and kinetics by intrinsically disordered proteins awarded by East Carolina University - Division of Research and Graduate Studies 2014
- Molecular Aspects of Copper and Zinc Promoted Prion-Prion Inera awarded by National Institutes of Health (NIH) 2008 - 2012
- Development of Prothymosin-Alpha-Derived anti-HIV Agents awarded by N.C. Biotechnology Center 2008 - 2009
- Molecular Aspects of Copper and Zinc Promoted Prion-Prion Interactions awarded by GOV-National Institutes of Health(NIH) 2008
- Development of prothymosin-alpha-derived anti-HIV agents awarded by North Carolina Biotechnology Center 2007
- Quantitating Prion-Derived Peptide Anchoring to Membranes by Nuclear Magnetic Resonance: A Key Step in Exploring Prion-Prion Interactions awarded by East Carolina Univsersity 2007
- Metal Cofactors in Natively Unstructured Proteins: Exploring Zn2+ Binding in Prothymosin awarded by American Chemical Society, The Petroleum Research Fund 2004 - 2006
- Metal Cofactors in Natively Unstructured Proteins: Exploring Zinc-Binding in Prothymosin-alpha awarded by Petroleum Research Foundation 2004
- Metal Cofactors in Natively Unstructured Proteins: What Binding Motifs Are Used By These Species And What Functions Do They Fulfill? awarded by East Carolina University 2004
- Gaining Structural Insight into Prothymosin-a's Role in Normal and Malignant Cell Proliferation: Exploring Zinc-Binding in Prothymosin-alpha awarded by PRI-American Cancer Society 2003
- Metal Cofactors in Natively Unstructured Proteins: Exploring Zinc-Binding in Prothymosin-alpha awarded by East Carolina University 2003
co-principal investigator on
investigator on
- NC Innovation Grant awarded by NCInnovation 2024 - 2026
- Development of a small-molecule immunomodulator for the treatment of melanoma awarded by Claradele Pharmaceuticals, Inc 2021 - 2026
- Improving Survival Rates of Metastatic Melanoma Using a Novel Immunotherapy Approach awarded by NCBC - North Carolina Biotechnology Center 2021 - 2024
- Deciphering the Function of the COOH Region of Troponin T in Normal Cardiac Function and Hypertrophic Cardiomyopathy awarded by Brody Brothers Fund 2014
- Targeting ER stress to induce selective toxicity using AEA and its novel metabolite, 15deoxy, delta12,14PGJ2-EA awarded by Golfers Against Cancer (GAC) 2013
- J-Series Prostaglandin-Ethanolamides as Novel Cancer Therapeutic Agents for Non-Melanoma Skin Cancer awarded by Division of Research and Graduate Studies 2013
Service
professional service activities
- Review manuscript for Biochimica and Biophysica Acta -- Molecular and Cell Biology of Lipids 2024
- Faculty Application for Advancement in Rank Served as an external reviewer for a faculty memberapplyingfor promotion to the rank of Professor in the Natural Sciences atthe University of South Carolina Beaufort. 2022
- Peptide Science Reviewed article 2021
- Biopolymers Reviewed article 2019
- Biochemistry Reviewed article 2018
- Biosystems Reviewed article 2018
- Polish Science Foundation Reviewed grant proposal 2018